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Esperal 250mg Tablet 10s Salt Information :

Side Effects of Esperal 250mg Tablet 10s:
esperal 250 mg side effects esperal 250 mg tablet Drowsiness, Fatigue, Lassitude, Psychotic Reactions, Peripheral And Optic Neuropathies, Hepatotoxicity, Garlic-Like Or Metallic After-Taste, GI Upset, Body Odour, Bad Breath, Headache, Impotence. Potentially Fatal: Respiratory Depression, CV Collapse, Arrhythmias, Myocardial Infarction, Acute CHF, Convulsions, Sudden Death.

Drug Interactions of Esperal 250mg Tablet 10s:

esperal 250 mg availability Inhibits Hepatic Enzymes Thus Interferes With Metabolism Of Other Drugs; Enhances Anticoagulant Effects Of Phenytoin And Coumarin. Adverse CNS Effects May Be Precipitated With Concurrent Metronidazole, INH Or MAOI Therapy. Tricyclic Antidepressants Exacerbate Symptoms Of Disulfiram Alcohol Reaction. Potentially Fatal: esperal 250mg online Disulfiram Alcohol Interaction: Intense Flushing Of Neck And Face Accompanied By Heat And Sweating, Tachycardia, Palpitation, Dyspnoea, Dizziness, Headache, HTN Initially And Then Hypotension; GI Disturbances, Exhaustion, Convulsions And Cardiopulmonary Arrest.

Contraindications of Esperal 250mg Tablet 10s:

Hypersensitivity, CVS Diseases; Peripheral Neuropathy, Psychosis. Not To Be Used In Patients With Alcohol Intoxication.

Mechanism of Action of Esperal 250mg Tablet 10s:

Disulfiram Inhibits Aldehyde Dehydrogenase, The Oxidative Enzyme Of Acetaldehyde, A Metabolite Of Alcohol. The Latter Is Accumulated In The Blood, Thus Producing Unpleasant Symptoms Of Disulfiram-Alcohol Reaction When A Patient Has Taken Small Amounts Of Alcohol. Onset: 12 Hrs. Duration: 1-2 Wk After Last Dose. Absorption: Rapidly Absorbed From The GIT; Peak Plasma Concentrations After 8-10 Hrs (Oral). Metabolism: Reduction To Diethyldithiocarbamate By The Glutathione Reductase System In The Erythrocytes. Excretion: Urine (As Metabolites); Exhaled Gas (Carbon Disulphide).

Special Precautions for Esperal 250mg Tablet 10s:

Diabetes, Epilepsy, Hepatic/Renal Impairment, Hypothyroidism, Cerebral Damage, Elderly. Liver Function And Blood Tests Should Be Monitored Regularly. Pregnancy And Lactation.

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